AI at the edge transforms wearables into THINKables offering continuous, cognitive, real-time analytics of patient data at the point of sensing. Customised sensing platforms play a key role in connecting monitoring systems directly with data management solutions and machine-learning technology for improved diagnosis, prognosis and management of disease and wellness. The session will explain technical and commercial backgrounds of these advanced patient monitoring systems to expert and non-expert audiences and highlight selected recent developments showcasing how they can be integrated in telehealth and virtual care applications.